Silica Spheres / Pellets / Beadlets / Granules


Silica
SILICA SPHERES SPRAYSPHERES™ - AS

Silica Spheres Neutral Spheres Consist of SiO2 and mainly used as a core for drug loading of insoluble and instable drug. Also used in MUPS technology.

Silica Spheres Definitions:
  • The SPRAYSPHERES™ - AS have been developed using Silicon dioxide (75%) as base.
  • Silica complying with Ph. Eur / USP / NF.
  • Manufacturing in accordance with the cGMP.
Silica Spheres General properties:
  • Nearly white hard, uniform and spherical particles. (sphericity degree average 90%)
  • Very low friability level.
Silica Spheres Particle Size Specifications:
  • Minimum of 96% (w/w) of SPRAYSPHERES™ - MS are between the lower and the upper limits of the size stated on the label.
  • The SPRAYSPHERS™ - AS selection is obtained by the decreasing size by sieving method.
Silica Spheres Application:
  • Minimum of 96% (w/w) of SPRAYSPHERES™ - MS are between the lower and the upper limits of the size stated on the label.
  • The SPRAYSPHERS™ - AS selection is obtained by the decreasing size by sieving method.
  • Used as cores to be coated in the manufacture of dry pharmaceutical forms. It enables greater accuracy and consistency in drug layering and coating.
  • Adopted to controlled release or sustained release formulations SPRAYSPHERES™ - AS make it easy to produce spherical micro granules which has the most suitable size and dissolution profile to each specific purpose.
  • Adapted for controlled release or Sustained release formulations to produce spherical granules or Spheres which have the most suitable size and dissolution profile.
  • Suitable for highly soluble active pharmaceutical ingredients.